Gastric Ulcer – types, symptoms, causes, diagnosis&treatment

What is a Gastric Ulcer? A gastric ulcer, also known as a stomach ulcer, is a sore or lesion that forms in the lining of the stomach. These ulcers occur when the protective mucus layer in the stomach becomes compromised, allowing stomach acid to erode the underlying tissues.

Types of Gastric Ulcers:

  1. Peptic Ulcers: These can develop in the stomach (gastric ulcers) or the upper part of the small intestine (duodenal ulcers).
  2. Acute Gastric Ulcers: Sudden onset ulcers typically caused by severe burns, injuries, or trauma.
  3. Chronic Gastric Ulcers: Long-term ulcers that persist for weeks or months, often associated with underlying conditions like H. pylori infection or prolonged use of NSAIDs.

Symptoms of Gastric Ulcers:

  • Burning or gnawing abdominal pain, typically between meals or at night
  • Nausea and vomiting
  • Bloating and abdominal discomfort
  • Loss of appetite and unintended weight loss
  • Dark or bloody stools
  • Fatigue and weakness

Causes of Gastric Ulcers:

  • Helicobacter pylori (H. pylori) infection: A common bacterial infection that weakens the stomach’s protective lining.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): Prolonged use of medications like aspirin, ibuprofen, or naproxen can irritate the stomach lining.
  • Excessive alcohol consumption: Alcohol can erode the stomach lining and increase stomach acid production.
  • Smoking: Tobacco use can impair blood flow to the stomach lining, delaying ulcer healing.
  • Stress and anxiety: While not a direct cause, stress can exacerbate ulcer symptoms and delay healing.

Diagnosis of Gastric Ulcers:

  • Upper endoscopy: A procedure to visualize the stomach lining and identify ulcers.
  • Biopsy: Tissue samples may be collected during endoscopy to test for H. pylori infection or rule out other conditions.
  • Barium swallow: X-ray imaging of the upper digestive tract after ingesting a barium solution to detect ulcers or other abnormalities.
  • Blood, stool, or breath tests: Used to detect H. pylori infection.

Treatment of Gastric Ulcers:

  • Medications: Proton pump inhibitors (PPIs) and H2-receptor antagonists to reduce stomach acid production and promote ulcer healing.
  • Antibiotics: Treatment for H. pylori infection if present.
  • Antacids: Over-the-counter medications to neutralize stomach acid and relieve pain.
  • Lifestyle changes: Avoiding NSAIDs, alcohol, and smoking, as well as managing stress through relaxation techniques or therapy.
  • Dietary modifications: Consuming smaller, more frequent meals and avoiding spicy or acidic foods that may exacerbate symptoms.