Heartburn (GERD) – Gastroesophageal Reflux Disease, risk& more

Introduction to Heartburn and GERD: Heartburn, also known as acid indigestion, is a common symptom of gastroesophageal reflux disease (GERD), a chronic condition characterized by the backward flow of stomach acid into the esophagus. It causes a burning sensation in the chest, often after eating or when lying down. Understanding the causes, symptoms, and treatment options for heartburn and GERD is essential for managing the condition and preventing complications.

Causes of Heartburn and GERD:

  1. Weak Lower Esophageal Sphincter (LES): The LES is a ring of muscle that acts as a valve between the esophagus and stomach. When it weakens or relaxes abnormally, stomach acid can reflux into the esophagus.
  2. Hiatal Hernia: A condition in which the upper part of the stomach protrudes through the diaphragm into the chest cavity, increasing the risk of acid reflux.
  3. Dietary Factors: Certain foods and beverages, such as spicy or fatty foods, citrus fruits, tomatoes, chocolate, caffeine, and alcohol, can trigger or worsen heartburn symptoms.
  4. Obesity: Excess body weight can increase pressure on the stomach and promote reflux of stomach contents into the esophagus.
  5. Smoking: Tobacco use can weaken the LES and impair esophageal function, leading to increased reflux symptoms.
  6. Pregnancy: Hormonal changes and increased abdominal pressure during pregnancy can contribute to acid reflux.
  7. Certain Medications: Some medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin, and certain blood pressure medications, can worsen heartburn symptoms.

Symptoms of Heartburn and GERD:

  1. Burning Sensation in the Chest: A feeling of discomfort or burning in the chest, often behind the breastbone, that may worsen after eating or when lying down.
  2. Acidic Taste in the Mouth: Sour or bitter taste in the mouth due to regurgitation of stomach acid.
  3. Difficulty Swallowing (Dysphagia): Sensation of food sticking in the throat or difficulty swallowing, especially solid foods.
  4. Regurgitation: Backward flow of stomach contents, including acid and food particles, into the mouth or throat.
  5. Chronic Cough: Persistent cough, particularly at night, may be a symptom of GERD-related irritation of the throat.
  6. Hoarseness or Sore Throat: Inflammation of the vocal cords or throat tissues due to acid reflux.
  7. Chest Pain: Chest discomfort that may mimic heart-related chest pain (angina) but is usually relieved by antacids or acid-suppressing medications.
  8. Worsening Symptoms When Lying Down or Bending Over: Acid reflux symptoms may worsen when lying down or bending over, particularly after meals.

Diagnosis of Heartburn and GERD:

  1. Medical History and Physical Examination: Evaluation of symptoms, medical history, and risk factors for GERD.
  2. Upper Endoscopy (Esophagogastroduodenoscopy, or EGD): Visual examination of the esophagus, stomach, and upper digestive tract using a flexible tube with a camera.
  3. Esophageal pH Monitoring: Measurement of acid levels in the esophagus over a 24-hour period to assess acid reflux.
  4. Esophageal Manometry: Measurement of pressure and muscle function in the esophagus to evaluate LES function.
  5. Barium Swallow Test: X-ray examination of the esophagus and stomach after swallowing a contrast material to detect structural abnormalities or reflux.

Treatment Options for Heartburn and GERD:

  1. Lifestyle Modifications:
    • Dietary Changes: Avoid trigger foods and beverages that worsen symptoms, such as spicy, fatty, or acidic foods.
    • Weight Management: Maintain a healthy weight through diet and exercise to reduce pressure on the stomach.
    • Elevate the Head of the Bed: Raise the head of the bed by 6 to 8 inches to prevent reflux during sleep.
    • Avoid Eating Before Bedtime: Allow at least 2 to 3 hours between eating and lying down to reduce nighttime reflux.
    • Smoking Cessation: Quit smoking to improve LES function and reduce reflux symptoms.
  2. Over-the-Counter (OTC) Medications:
    • Antacids: Neutralize stomach acid and provide temporary relief from heartburn symptoms.
    • H2 Receptor Antagonists: Reduce acid production in the stomach and provide longer-lasting relief than antacids.
    • Proton Pump Inhibitors (PPIs): Block acid production in the stomach and promote healing of esophageal inflammation.
  3. Prescription Medications:
    • Stronger doses of H2 blockers or PPIs may be prescribed for severe or persistent GERD symptoms.
  4. Surgery:
    • Fundoplication: Surgical procedure to reinforce the LES and prevent acid reflux by wrapping the top of the stomach around the lower esophagus.
    • LINX Reflux Management System: Minimally invasive procedure involving implantation of a magnetic ring around the LES to prevent reflux while preserving normal swallowing.